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Genomics and the Exoneration of Patient Zero

His name was Gaëtan Dugas. He was a Canadian flight attendant infected with the HIV virus who succumbed to AIDS in 1984. Through misinterpretation and shoddy reporting of early CDC research on the disease, Dugas came to be labeled Patient Zero and identified as “the man who gave us AIDS.” In 1987, reporter Randy Shilts vilified him as a sociopath in his book And the Band Played On. Soon the story was disseminated by 60 Minutes and other news sources.

However, researchers using cutting edge methods to sequence eight full-length viral genomes from the 1970s, have published their findings in Nature and cleared Dugas’ name. According to journal editors, analyses conducted by Michael Worobey and colleagues “suggest that the virus was introduced to New York City around 1970 and that by 1979 the epidemic was already relatively mature and genetically diverse.” While Dugas was at the center of a particular cluster of cases, thousands of men already had the misfortune of being infected with the virus in New York and San Francisco at the time.

Read more about it:

Worobey, M., Watts, T. D., McKay, R. A., Suchard, M. A., Granade, T., Teuwen, D. E.,… Jaffe, H. W. (2016). 1970s and
‘Patient 0’ HIV-1 genomes illuminate early HIV/AIDS history in North America.  Nature, 539(7627), 98-101.
doi:10.1038/nature19827
Available at http://tinyurl.com/dugaszero
(Villanova LDAP ID and password required)

NPR Story

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Shilts’ book available at Falvey Library.

 

 

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APA Style giving you or your students problems?

These short videos can help:

APA Demystified: Citing Journal Articles

APA Demystified: In-Text Citations

APA Demystified: Citing Web Pages, Books, Book Sections

Questions? Need more help? Contact Barbara

 

 


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Falvey Memorial Library Presents: Info to Go at Driscoll Hall

Robin Bowles, research help, info to go, Driscoll Hall

Librarian Robin Bowles is all smiles with the crash cart!

Falvey Memorial Library is on the move. Research and Instruction Librarian Robin Bowles and Nursing Librarian Barbara Quintiliano are offering research assistance in Driscoll Hall to students! So, grab some research help with that cup of coffee. Look for the crash cart staffed by Robin or Barbara on Tuesdays and Thursdays in the Driscoll Hall café from 11:00 a.m.-1:00 p.m. The rest of the day they can be found in Driscoll Hall room 343. Ask them anything. Seriously. They can get you stats, pertinent journal articles for a paper or just help you find the odd fact from a reputable source. Research life support is their specialty! (Added bonus: they always have free chocolate and pens!)

Barbara and Crash Cart

Librarian Barbara Quintiliano helps two students find the resources they need.


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Nursing students & social media / Hunting for drugs to combat Zika

Facebook, Instagram, Snapchat, text messaging….so many ways to stay in touch and share information with friends.  However, nursing students need to be aware of the ethical and legal ramifications surrounding the use of social media during their clinical experience.  Patient confidentiality is only one of several important factors to consider.  The ANA Code of Ethics for Nurses with Interpretive Statements (2015 e-book ed. available through Falvey Library) specifically addresses the issue of social media use.  Court cases have ensued!

Here’s an article on the topic you may wish to share with your students:

Westrick, S. J. (2016). Nursing students’ use of electronic and social mMedia: Law, ethics, and e-professionalism. Nursing Education Perspectives, (1), 16-22. doi:10.5480/14-1358

Click to access.

Fighting the Zika Virus

Read a recent article in Nature Medicine reporting on the hunt for antivirals to combat the Zika virus:

Kincaid, E. (2016). A second look: Efforts to repurpose old drugs against Zika cast a wide net. Nature Medicine, 22, 822-825. doi:10.1038/nm0816-824

Click to access.

Here’s a research article, also from Nature Medicine, on investigators’ discovery that niclosamide, a medication commonly used to treat tapeworm, has shown promise in preventing the replication of the Zika virus in the fetal brain.

Research questions?  Contact Barbara


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An Author of Few Words

Barbara Quintiliano with Some Favorite Things

Barbara Quintiliano with Some Favorite Things

What kind of story can you tell in six words? Just ask Barbara Quintiliano, nursing/life sciences and instructional services librarian. She’s an expert at this, having posted 2,225 memoirs so far under her pen name, liberata. Smith Magazine selected Quintiliano as their March 2016 memoirist of the month. March marks her third anniversary with Six Word Memoirs, a project of the online Smith Magazine.

Quintiliano says, “I mean, who can’t write six words? It’s easy and so much fun … Gotta keep on sixing!” One of her six-word memoirs, “Don’t make life a preemptive strike,” is published in The Best Advice in Six Words (released November 2015). The book includes 1,000 contributions including those of celebrities such as Whoopi Goldberg, Molly Ringwald and Lemony Snicket, and Falvey’s own celebrity writer.

Some examples of her other six-word memoirs: “OK, putting my self-doubt to bed,” “Seeking hardcover-wisdom in a Kindle world,” “Progress. Said no to someone today,” “Coffee’s the only weapon I need,” and most appropriate for the six-word format, “I’m really good at doing succinct.” She explains her interest in the Six-Word Memoirs as an outgrowth of her life-long interest in writing in journals, having pen pals and, more recently cyber pals (email).

Quintiliano and Rob LeBlanc, first-year experience/humanities librarian, recently published an article, “Recycling C.R.A.P.:  Reframing a Popular Mnemonic for Library Instruction,” in Pennsylvania Libraries: Research and Practice, volume 3, number 2 (Fall 2015). In 2009 Quintiliano won the Facultas Award.

What is Smith Magazine? It is an online magazine founded and edited by Larry Smith. The magazine is best known for its Six-Word Memoir® project, which Smith launched in November 2006 by asking, “Can you tell your life story in six words?” The challenge became popular with more than one million Six-Word Memoirs published to date.

Before creating Smith Magazine, Larry Smith was an articles editor of Men’s Journal. He had also held other editorial positions and has published articles in The New York Times, Popular Science, Men’s Health, and others.

Who really wrote the first six word memoir? Actually Julius Caesar did it in three words: “Veni, vidi, vici” which translates into six English words: “I came, I saw, I conquered.” Was this Smith’s inspiration? Perhaps, but there is also a legend that Ernest Hemingway was challenged to write a six word story. His answer, “For sale:  baby shoes, never worn.” What ever the answer, the challenge is popular!


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Zika Virus News & Data You Can Reuse

Recent articles on the Zika virus

zika_womanBrasil, P., Pereira, J. P.,Jr, Raja Gabaglia, C., Damasceno, L., Wakimoto, M., Ribeiro Nogueira, R. M., . . . Nielsen-Saines, K. (2016, March 4). Zika virus infection in pregnant women in Rio de Janeiro – preliminary report. New England Journal of Medicine, doi:10.1056/NEJMoa1602412 [doi]
http://ezproxy.villanova.edu/login?URL=http://www.nejm.org/doi/10.1056/NEJMoa1602412

Marrs, C., Olson, G., Saade, G., Hankins, G., Wen, T., Patel, J., & Weaver, S. (2016).
Zika virus and pregnancy: A review of the literature and clinical considerations.
American Journal of Perinatology, doi:10.1055/s-0036-1580089 [doi]
https://www.thieme-connect.com/DOI/DOI?10.1055/s-0036-1580089

Other recent articles listed in RefWorks format.
http://tinyurl.com/zikaarticles

Click the Find it button to check for full text. Click the double helix icon to the right of the title to read the PubMed abstract.
Image credit: http://www.paho.org/

Data you can use and reuse

Data want to be free, and as members of the Villanova University community, you
have access to entire series of health-related data via the ICPSR database.

icpsr2

Most of these data sets are available in SPSS, SAS, STATA and other data formats. Check them out!

Health and Medical Care Archive (Robert Wood Johnson Foundation)
http://ezproxy.villanova.edu/login?URL=http://www.icpsr.umich.edu/icpsrweb/HMCA/index.jsp

AHRQ MCC Research Network Data Archive
http://ezproxy.villanova.edu/login?URL=http://www.icpsr.umich.edu/icpsrweb/AHRQMCC/

National Addiction & HIV Data Archive Program (Office of Behavioral and Social Sciences Research, NIH)
http://ezproxy.villanova.edu/login?URL=http://www.icpsr.umich.edu/icpsrweb/NAHDAP/

Integrated Fertility Survey Series (Eunice Kennedy Shriver National Institute of Child Health
& Human Development,
Population Studies Center)
http://ezproxy.villanova.edu/login?URL=http://www.icpsr.umich.edu/icpsrweb/IFSS/

National Archive on Computerized Data on Aging (National Institute on Aging, NIH)
http://ezproxy.villanova.edu/login?URL=http://www.icpsr.umich.edu/icpsrweb/NACDA/index.jsp

Genomic Data and Biomarkers (Eunice Kennedy Shriver National Institute of Child Health
& Human Development)
http://www.icpsr.umich.edu/icpsrweb/content/DSDR/genomic.html
Image credit: http://www.icpsr.umich.edu

Questions? Comments? Contact Barbara


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Zika Virus Information

Video from the Pan American Health Organization (PAHO)
Zika, a New Threat. What Is It (in Spanish with English subtitles)
https://youtu.be/M8mWDIPKW28

 

Excerpt from Zika virus spreads across Americas as concerns mount over birth defects. (2015). BMJ, 315, h6983.
doi: http://dx.doi.org/10.1136/bmj.h6983

Zika’s rapid geographic spread would be causing less concern to public health authorities were it not for worrying evidence that the disease is less benign than initially thought. Hundreds of cases of Guillain-Barré syndrome have sprung up in the wake of Zika infection, but it is an explosion of microcephaly among infants born to infected women that has caused Brazil to declare Zika a “public health emergency of national importance.”

 

Basic info on Zika

According to PAHO, “Zika fever is a mosquito-borne viral disease caused by Zika virus (ZIKV), consisting of mild fever, rash (mostly maculo-papular), headaches…and non-purulent conjunctivitis, occurring about three to twelve days after the mosquito vector bite. One out of four people may develop symptoms, but in those who are affected the disease is usually mild with symptoms that can last between two and seven days. Its clinical manifestation is often similar to dengue, also a mosquito-borne illness.”
http://www.paho.org/hq/index.php?option=com_topics&view=article&id=427&Itemid=41484&lang=en

There is currently no vaccine or specific treatment for Zika virus infection. Therefore, treatment for everyone, including pregnant women, is directed at alleviating symptoms.
http://www.paho.org/hq/index.php?option=com_content&view=article&id=11552&Itemid=41672&lang=en

Factsheet from the World Health Organization (WHO)
http://www.who.int/mediacentre/factsheets/zika/en/

How does Zika virus affect pregnant women and fetuses?

Fetuses exposed in utero to the Zika virus are at risk for microcephaly, a condition where a baby’s head is much smaller than expected. Babies with microcephaly can suffer from various problems, such as developmental delay, intellectual disability, hearing loss, and vision problems.

More about microcephaly
http://www.cdc.gov/ncbddd/birthdefects/microcephaly.html

Travel Alert (Centers for Disease Control and Prevention)

The CDC recommends special precautions for pregnant women and women trying to become pregnant. These women should consider postponing visits to countries currently affected by Zika virus transmission. Included are the countries of Brazil, Colombia, El Salvador, French Guiana, Guatemala, Haiti, Honduras, Martinique, Mexico, Panama, Paraguay, Suriname, Venezuela, and the Commonwealth of Puerto Rico.
http://www.cdc.gov/media/releases/2016/s0315-zika-virus-travel.html

CDC Zika Website
http://www.cdc.gov/zika/

Journal articles available on the topic of the Zika virus outbreak (Click Find it to check for full text availability.)
http://tinyurl.com/zikavirus

Barbara Quintiliano, Nursing/Life Sciences Librarian
(610-519-5207)
More Nursing blog features


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Find out who’s talking about you

  • Posted by: Barbara Quintiliano
  • Posted Date: November 19, 2015
  • Filed Under: Nursing
  • Tags:

Want to know who is citing articles that you’ve written?  Here are three ways to find out who’s talking about you: Science Citation Index Expanded, Scopus, and Google Scholar. (more…)


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PDA is Pretty Darned Awesome!

  • Posted by: Barbara Quintiliano
  • Posted Date: October 6, 2015
  • Filed Under: Nursing
  • Tags:

It’s the latest thing in library collection development: PDA or patron-driven acquisition, also called DDA (demand-driven acquisition). Instead of purchasing materials “just in case” users may wish to read them in the future, materials are acquired “just in time,” that is, at point of demand. Many PDA plans are automatic. If one or more users try to access portions of an ebook beyond the table of contents, a purchase is triggered and the content is instantaneously available.  Other plans are mediated.  This means that the librarian is sent a report of attempts to access content, allowing her to gauge interest in the title. She can then decide whether or not to place an order for the ebook.

Falvey Library has recently instituted a mediated PDA plan through Rittenhouse Book Distributors for the more than 150 ebooks comprising the Doody’s Core Nursing Collection. A Doody’s Core title “is a book or software title that represents essential knowledge needed by professionals or students in a given discipline and is highly recommended for the collection of a library that serves health sciences specialists.”

For the list of Doody’s Core Titles in nursing, click here.

The plan works like this:
Metadata for the items are preloaded into the library’s online catalog.  “Connect to this resource online” allows users to view the table of contents and to attempt to access portions of the book. The nursing librarian receives weekly email notifications of these attempts. From the number of attempts reported she can decide whether or not to order the ebook as a permanent addition to the collection.

Pretty darned amazing when you think about it!

Questions? Comments! Contact Barbara.

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ANA Scope and Standards Online

Welcome back, College of Nursing faculty, staff and students!

Falvey Library has acquired electronic versions of the following ANA Scope and Standards:

Addictions Nursing
https://library.villanova.edu/Find/Record/1535292

Holistic Nursing
https://library.villanova.edu/Find/Record/1535295

Home Health Nursing
https://library.villanova.edu/Find/Record/1535294

Nursing Informatics
https://library.villanova.edu/Find/Record/1535293

Public Health Nursing
https://library.villanova.edu/Find/Record/1535296

The text is in pdf format and can be downloaded…from anywhere!  Electronic versions of other ANA standards will be acquired as they become available.

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Questions welcome at the research cart!

robin_saira_verysm

Please let your students know that Robin and Barbara are just waiting for them to drop by and ask us questions.  We’re stationed at ye ol’ research cart in the Driscoll Café  on Tuesdays and Thursdays from 11 am till 1 pm.  Students are also welcome to stop by our office in Driscoll 343 on those days. And we’re available at Falvey Library Monday, Wednesday and Friday.

No question too trivial or too monumental. Put us to the test!

Videos that take a bite out of students’ APA style problems!

Here are three short videos (about 3 min each) that your students can view (and re-view) whenever they need assistance with common elements of APA 6th Style:

APA Demystified: Citing Journal Articles
http://tinyurl.com/apacitearticles

APA Demystified: In-Text Citations
http://tinyurl.com/apaciteintext

APA Demystified: Citing Web Pages, Books, Book Sections
http://tinyurl.com/apacitebooksweb

Spread the good word!

Questions?  Need more information?  Contact Barbara


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Congratulations to Falvey Scholars!

Congratulations to the following Falvey Scholars chosen from among several worthy College of Nursing candidates!  And congratulations to their faculty mentors!

Katie Kline on “What to Know About Home Genetic-Test Kits.” Mentor: Dr. Theresa Capriotti, DO, MSN, RN, CRNP

Katie investigated the growing use of these kits, which can be purchased at local pharmacies as well as online.  The producers of the kits claim that by sending them a DNA sample (taken from saliva or the inside of the cheek) individuals can receive a report on ancestry/paternity, drug reactions, and susceptibility to genetic diseases. However, the results raise more questions than they answer, and the reliability and confidentiality of the testing are also in doubt.

Elizabeth Long on “Nurses’ Perceptions of Human Trafficking in an Urban Emergency Department: A Qualitative Study.” Mentor: Dr. Elizabeth B. Dowdell, RN, PhD, FAAN

Elizabeth interviewed a small sample of ED nurses at a major teaching hospital in Philadelphia to find out their perceptions of patients who present with injuries and who may possibly be victims of domestic violence or human trafficking.  She found that while ED nurses are very aware of the existence of human trafficking in the region, most do not recognize trafficked patients as such when they come for emergency treatment.

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Best wishes to our CON students who will be taking exams soon, and congrats to our soon-to-be graduates!

Need research assistance for yourself or a student?  Contact me.


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Last Modified: April 24, 2015